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KMID : 1134819960250060958
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Journal of the Korean Society of Food Science and Nutrition
1996 Volume.25 No. 6 p.958 ~ p.962
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Effect of Methanolic Extract of Pachymeniopsis elliptica on Lipids Component of Hyperlipidemic Rats
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Park Jong-Cheol
Jang Young-In
Do Myoung-Sool
Kim Seok-Hwan
Choi Jong-Won
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Abstract
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Hypolipidemic effect of methanolic extract of marine algae, Pachymeniopsis elliptica was examined in hyperlipidemic rats. Male Sprague-Dawley(l20±5g) rats were divided into five groups and fed high fat diets for four weeks. Each group was orally administered with methanolic extract of P. elliptica (PEM, 250, 500㎎/㎏), benzofibrate(BZF, 30㎎/㎏) and cholestyramine resin(CSR, 100㎎/㎏) daily for one week. Significant decreases in cholesterol, total lipid and triglyceride of both blood and liver were observed by the administration of the extract. But the levels of LDL- and HDL-cholesterol and the activity of lipase were not changed. Such results suggest that the extract may promote the fecal excretion of bile acid in hyperlipidemic rats.
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KEYWORD
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maline algae, Pachymeniopsis elliptica, hypolipidemic, cholestyramine resin
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